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This improvement was accompanied by a significant reduction in high-sensitivity CRP concentration, suggesting that the antiinflammatory effects of GLP-1 medicines may contribute to or be independently associated with their benefits in OSA

DPP-4 inhibitors raise levels of these hormones, which include glucose-dependent insulinotropic polypeptides (GIP) and glucagon-like peptide-1 (GLP-1)

However, off-label prescribing carries important considerations

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[14] [39] In December 2025, the FDA approved an oral version of semaglutide for weight management, using the same brand name (Wegovy) as the injectable version