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Description
Liraglutide, a glucagon-like peptide-1 receptor agonist, suppresses osteoclastogenesis through the inhibition of NF- B and MAPK pathways via GLP-1R
Patients with T2D with stable CAD presented an improvement in endothelial function expressed by an increase in flow-mediated vasodilation of the brachial artery, independent of changes in systolic and diastolic blood pressure during a hyperinsulinemic clamp in response to GLP-1 [35]
Market analysts have flagged this as a potential differentiator for next-generation therapies [18, 24]
10.1111/bph.15647 11 BossartM.WagnerM.ElvertR.EversA.HbschleT.KloeckenerT.et al (2022)
CAP-induced TRPV1 calcium responses were again inhibited by pretreatment with GLP-1 analogs or exendin 939 (Fig
