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Description
The real-world effectiveness gap between trials and practice Clinical trials measure efficacy (does the medication work under ideal conditions)
But tirzepatide may have a higher ceiling for appetite control when maximum doses are reached

These effects are typically mild to moderate, transient, and significantly reduced by starting at a low dose and titrating gradually

Let's cut through the bro-science and figure out when these compounds actually belong in your protocol

10.1186/s13020-025-01169-z
