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Some users report mild injection site reactions

In the AMPLITUDE-O trial, 15% of patients included were also receiving sodium-glucose cotransporter 2 (SGLT2) inhibitors, yet efpeglenatide decreased the rate of MACE irrespective of whether patients were also receiving this treatment
This also indicated a fundamentally different metabolic and endocrine response to caloric deficit in males versus females

Visceral Fat Redistribution Menopause often shifts fat storage from subcutaneous areas to visceral abdominal depots, even when total body weight remains stable
