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It is not known if dulaglutide will cause thyroid tumors, or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in people

If kidney function is impaired, the risk of lactic acidosis becomes even higher
And for a significant number of women, the side effects are intolerable or not worth it given their disappointing weight loss results

These follow the same pattern seen with all GLP-1 receptor agonist medications

Regular lab monitoring confirms methotrexate efficacy throughout treatment