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Their primary mechanisms of action include: Stimulating insulin secretion in a glucose-dependent manner (reducing hypoglycaemia risk) Suppressing glucagon release when blood glucose is elevated Slowing gastric emptying, which prolongs satiety Acting on appetite centres in the brain to reduce food intake Common GLP-1 medicines available in the UK include semaglutide (Ozempic, Wegovy), liraglutide (Victoza, Saxenda), and dulaglutide (Trulicity)

As cardiologists and intensivists, we need to be critical of the tracings themselves, avoid anchoring to a single value, and be observant of the overall hemodynamic trajectory our patient is taking

Recommended areas: the front of the thighs , abdomen (stomach area) , or upper arms

Side Effects and Long-Term Considerations Semaglutide, like any medication, may have potential side effects and long-term considerations that individuals should be aware of before starting treatment

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