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Several indirect mechanisms may contribute to fatigue in patients taking GLP-1 receptor agonists

[DOI] [PubMed] [Google Scholar] 105

"For the newer GLP-1 medications, it would be useful to look at whether there are genetic variants, like the variants in PAM , that explain poor responders to their medications." "There are a whole class of medications that are insulin sensitizers, so perhaps we can develop medications that will allow people to be sensitized to GLP-1s or find formulations of GLP-1, like the longer-acting versions, that avoid the GLP-1 resistance." The research has been published in Genome Medicine .

This natural hormone is produced by your body and is designed to reduce appetite, reduce food cravings, slow stomach emptying, and aid in regulating your blood sugar

A lower dose than expected is unlikely to have side effects