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Similarly, a six-month study of 790 overweight or obese antipsychotic-treated patients found an average weight reduction of 13.2 lb with liraglutide versus placebo and reduced HbA1c (Whicher CA et al, Diabetes Obes Metab 2021;23(6):12621271)

doi: 10.1016/j.bbrc.2017.11.076 75 YinW.JiangY.XuS.WangZ.PengL.FangQ.et al

By reducing the breakdown of peptide tyrosine tyrosine (PYY) 136, the amounts of the appetitesuppressing metabolite PYY 336 are lowered