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doi: 10.1111/j.1463-1326.2012.01676.x

Metformin has a known GI effect that tends toward looser stools in some patients, which can partially offset GLP-1-related constipation

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124,142 Investigations into mechanism of action-mediated pharmacokinetic DDIs are currently limited to those mediated by the slowing of gastric emptying, with examples summarized in other reviews
