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For people who discover an unexpected pregnancy while on tirzepatide, the situation detailed in our guide on pregnancy on tirzepatide provides the specific guidance needed

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Starting in January 2025, Ozempic gained FDA approval for reducing kidney disease risks in adults with type 2 diabetes who also have chronic kidney disease

A generic manufacturer could theoretically produce a different semaglutide formulation today without violating the expired composition patent, but they'd need to design around the active formulation patents, complete FDA approval (a 2-3 year process), and avoid triggering patent infringement litigation

A key limitation of this review is the absence of a formal risk of bias or quality grading tool, which is typically not required for narrative reviews