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, Phase 3 Trial of Semaglutide in Metabolic Dysfunction-Associated Steatohepatitis, New England Journal of Medicine (2025)

This is similar to the results reported for Mounjaro in the SURMOUNT-1 trial, where 36.2% of participants taking the highest (15mg) dose also lost at least 25% of their body weight

Some people notice less hunger within days

However, intraduodenal administration of an amino acid mixture effectively stimulates GIP release in healthy individuals [72]

With obesity affecting nearly 100 million individuals in the United States, the availability of effective oral pharmacotherapy may significantly expand the obesity treatment market