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Methotrexate is contraindicated in pregnancy and breastfeeding

However, detection and treatment of maternal subclinical hypothyroidism has also not been shown to cause improved pregnancy outcome and neurocognitive function in offspring [89,90]

Tell your healthcare provider right away if you get symptoms of gallbladder problems, which may include: pain in your upper stomach (abdomen), yellowing of skin or eyes (jaundice), fever, and clay-colored stools food or liquid getting into the lungs during surgery or other procedures that use anesthesia or deep sleepiness (deep sedation)

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