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One review defined it as heightened and/or persistent manifestations of food cue reactivity, often leading to food-related intrusive thoughts and maladaptive eating behaviors. In practice, this can mean mentally running through meals all day, repeatedly checking food delivery apps, or thinking about dinner before finishing lunch

However, several observations do not support general BBB permeability, including the limited brain access observed with fluorescently labeled semaglutide in the present study, together with analogous results with GLP-1 (35) and liraglutide (8)

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