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Sleep and stress : Inadequate sleep (less than 7 hours nightly) disrupts hormones that regulate hunger and satiety, including leptin and ghrelin, potentially counteracting semaglutide's effects
This imbalance results in an increased quantity of GLP-1R on the cell surface, amplifying intracellular signaling and insulinotropic properties
Diabetologia 67 , 24712480 (2024)
