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The primary endpoint was change in bodyweight from baseline at 24 weeks, with 48 weeks included as a secondary outcome
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2.3.2 Gut microbiota and its metabolites modulate GLP-1 secretion Emerging evidence highlights a bidirectional regulatory interplay between the gut microbiota and GLP-1, whereby microbial composition and metabolites exert profound influences on GLP-1 synthesis, secretion, and signaling
