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Liraglutide lowers blood sugar and body weight to a lesser extent than newer GLP-1s

The final section synthesizes these insights into a decision framework for distinguishing peptide systems that merit renewed investment from those that should remain abandoned and articulates a forward-looking perspective on the future of peptide therapeutics

Their findings were striking: AKD patients treated with GLP-1 RAs experienced lower rates of major adverse kidney events (MAKEs), which include complications like the need for dialysis, worsening kidney function, and even death due to kidney failure

EZGLP1T-36K

37 Given the promising results of semaglutide 2.4 mg, the phase 3b STEP-UP trial compared intensified semaglutide 7.2 mg with semaglutide 2.4 mg in adult patients with a BMI of 30 kg/m 2 and above, without diabetes