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Adicionalmente, caso o sintoma ocorra durante o aumento progressivo da dose, o estudo recomenda estender o uso da menor dose por mais algumas semanas e evitar o aumento da dose na vigncia de sintomas gastrointestinais
Randall-Selitto Test (RST) To assess mechanical hyperalgesia, the RST was implemented

The constipation effect typically peaks during dose escalation phases and often improves as your body adapts over 4 to 8 weeks

Mosenzon, M

Digestive side effects are often most noticeable after starting Zepbound or after increasing the dose
