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Weight regain following discontinuation of these medications is common (Figure 2), with up to two-thirds of weight loss being regained within the first year 24

Pick a subcutaneous site: abdomen (avoid 2 inches around the navel), front or outer thigh, or back of the upper arm

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Clinical studies of brand-name tirzepatide documented similar gastrointestinal side effects, with some differences in frequency and severity compared to semaglutide

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