tirzepatide journal club SURMOUNT-1 Trial 60-Second Journal Club: The SUMMIT

A history of pancreatitis Pancreatitis (inflammation of the pancreas) has been reported in people on GLP-1 medications, though its uncommon and the absolute risk increase is small

This change in appearance is usually due to a reduction in fat as a result of losing weight

If appetite suppression fades significantly between doses or fails to appear at a given dose level, that information helps guide escalation decisions

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While exercise is beneficial for diabetes management and weight loss, patients should avoid sudden intense exertion during the first weeks of therapy or after dose increases