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Route of Elimination Orsema SC Injection 0.5 mg/0.375 ml is primarily metabolized in the liver through proteolytic cleavage and is then excreted mainly through the urine

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Wang J, Leclercq I, Brymora JM, et al

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Reported cognitive symptoms may relate to hypoglycaemia, rapid weight loss, dehydration, or gastrointestinal side effects rather than direct drug effects

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