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Route of Elimination Orsema SC Injection 0.5 mg/0.375 ml is primarily metabolized in the liver through proteolytic cleavage and is then excreted mainly through the urine

Wang J, Leclercq I, Brymora JM, et al

Reported cognitive symptoms may relate to hypoglycaemia, rapid weight loss, dehydration, or gastrointestinal side effects rather than direct drug effects

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