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Maintaining weight loss remains a challenge with GLP-1 drugs, as many patients experience weight regain once the treatment is discontinued or after prolonged use

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These SCFAs bind to specific receptors on L-cells, notably the free fatty acid receptors FFAR2 and FFAR3, which directly stimulate GLP-1 secretion

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CNS delivery and target engagement

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Eli Lilly says Foundayo will be available more broadly across US retail pharmacies and telehealth providers shortly after that

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