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As TPAs have access to extensive claims data and analytics, theyre well-equipped to identify trends in the use of GLP-1s and assess the best, most affordable path forward

Amy Schroeder Principal Research Scientist | July 9, 2025 Current Landscape Overview Glucagon-like peptide-1 (GLP-1) receptor agonists (RAs) are an emerging drug class that are mostly indicated to improve glycemic control in patients with type 2 diabetes mellitus (T2D) and reduce body weight

Revise all quality agreements to include nitrosamine clauses Define escalation pathways and notification timelines Include nitrosamines in supplier audits Train procurement and QA on accountability boundaries Maintain documented oversight of supplier compliance If not done

Similarly, when abliglutide was used in patients with known HFrEF, no improvement was noted in LVEF (left ventricular ejection fraction) [28]

A Note on the Rollout: Please Be Patient with Us We now have meaningful clarity on the Bridge prior authorization process, as outlined above