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Understanding what each agent is and what it is not is essential before drawing any meaningful comparison

Together, these data suggested that activating GLP-1R alleviated glycolysis, at least partially by the suppression of PFKFB3-driven glycolysis, and attenuated lactate-mediated histone lactylation, which in turn suppressed the transcription of profibrotic genes in TGF-1 + IL-1-challenged fibroblasts

Supplementary Table 5 Complete list of kidney outcomes assessed

or c) have a BMI between 27 and 30 plus at least one weight-related health condition, such as cardiovascular disease, high blood pressure, or high cholesterol