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Inhibiting COX-1 increases the risk of stomach ulcers and GI bleeding

Gastroenterology & hepatology , 5 (10 Suppl 18), 416

doi: 10.2903/j.efsa.2021.6780 34 EverardA.BelzerC.GeurtsL.OuwerkerkJ

Once you have reached your target weight, lower doses are sufficient to prevent regain

Participants typically begin on a low starting dose, which is gradually increased over a period of weeks or months under medical supervision
