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New FDA regulations and legal actions are phasing out compounded GLP-1s, while companies introduce lower-priced, FDA-approved alternatives.

While newly approved pharmacotherapies such as glucagon-like peptide-1 receptor agonists (GLP-1 RAs) show efficacy, their clinical utility remains constrained by dose-dependent gastrointestinal complications, underscoring the urgent need for safer alternatives

Recent evidence suggests these drugs also benefit heart, kidney, liver, and even brain health.

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