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Whether the positive impact of GLP-1RAs on hepatic histology is indirect, i.e., through their action on extrahepatic tissues, or whether their action is direct, i.e., through activating GLP-1R on the hepatocytes, is still a controversial issue
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Berberine and semaglutide both target metabolic pathways, but combining them requires careful consideration

Pale yellow urine Light yellow urine indicates adequate hydration and proper urine concentration

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