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Description
This condition commonly affects people with metabolic conditions, including obesity, high blood pressure, and type 2 diabetes
Incretin-based drugs and the incidence of endometrial cancer among people with type 2 diabetes: active comparator new-user design

Slow titration of dose can help, as can dietary adjustments. The recent mast cell paper suggested: significantly lower doses of GLP-1RAs than presently used as starting doses for T2DM and obesity therapy might be sufficient, and even optimal, for MCAS

[DOI] [PMC free article] [PubMed] [Google Scholar] 21.Chen X.Y., Chen L., Yang W., Xie A.M
The downstream pathways are mainly the PI3K and MAPK pathways
