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The irony is brutal

Pyrimidinedione derivatives, known for enhanced metabolic stability, led to the potent, selective, and bioavailable DPP-4 inhibitor alogliptin

in: PubMed | Google Scholar | 1 Ted Rogers Centre for Heart Research, University of Toronto, Toronto, Ontario, Canada

Furthermore, in human studies, GLP-1 infusion has been shown to slow gastric emptying and increase fasting and postprandial gastric volume [45]

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