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I stayed on 0.25 dose for the second month but may request 0.50 mg next month. Starting to see results after one month

Protecting the skin with sunscreen and moisturizers can help minimize weather-related triggers

Medically reviewed by Alan Lucks | MD , Alan Lucks MDPC Private Practice - New York on October 24th, 2025

PlexusDx offers a lower starting dose option (Microdose GLP-1 Protocol at $129/mo) and the Precision Peptide Genetic Test ($99 add-on) to identify metabolic factors that may increase cold sensitivity risk

Your doctor might recommend one GLP-1 agonist over another based on factors like your insurance coverage and specific symptoms