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Their use in PCOS fertility care should be individualized through shared decision-making, with explicit discussion of the difference between established metabolic benefit and hypothesis-generating reproductive benefit, together with drug-specific washout planning and strategies to minimize post-discontinuation rebound

Understanding Retatrutide Retatrutide is a next-generation weight loss drug currently in late-stage development that imitates three gut hormones: GLP-1, GIP, and glucagon that can influence appetite and metabolism

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