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This follows results from the STEP 2 and STEP 8 extension studies, where the 7.2 mg dose demonstrated superior weight loss and better weight maintenance compared to the currently approved 2.4 mg dose

Additionally, if CV risk was managed upstream through weight reduction, unmet need due to high residual CV risk would likely manifest itself in specific patient sub-segments and thus require innovators to take a highly targeted approach in both clinical development and commercialisation