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In primary human hepatocytes, adiponectin can also increase MMP-9 mRNA and enzymatic activity [184], which plays a bidirectional regulatory role in different fibrotic diseases or different stages of the same fibrotic disease [115]

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The quality and effectiveness of compounded medications vary due to less rigorous safety checks than FDA-approved medications

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Therefore, early discovery and motions will focus on addressing whether the claims are pre-empted by federal law, and whether plaintiffs must provide specific gastroparesis diagnostic testing evidence in the Ozempic, Wegovy and Mounjaro lawsuits

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