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Description
Severe kidney or liver disease
Adipose tissue failure forces the spillover of excessive free fatty acids (FFA) into the systemic circulation, causing ectopic fat deposition in non-adipose organs, including the skeletal muscle and, critically, the liver ( de novo lipogenesis and endogenous glucose production, thereby driving both hepatic steatosis and hyperglycemia
Theres excitement about its potential impact on cholesterol, fatty liver, and heart health, which adds layers to its value in the clinic
Endocrine regulation of male fertility by the skeleton
Giugliano, Insulin and glucagon-like peptide 1 receptor agonist combination therapy in type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials
