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When To Contact Your Clinician Without Delay It requires immediate contact with your physician if you experience: Severe or persistent abdominal pain Persistent vomiting or diarrhea causing dehydration Fever with severe abdominal pain Signs of low blood sugar that you cannot manage Sudden bile duct type symptoms Allergic reactions at the injection site or system-wide Realistic Expectations Without Promises Link Individual response varies, and long-term safety beyond trial periods needs more data

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However, it is only a matter of time before we will have more definitive answers

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Over two years of follow-up, tirzepatide was linked to greater weight loss overall