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GLP-1(9-36) has also been demonstrated to promote cardiac glucose uptake similar to GLP-1(7-36)-amide (90), so the descriptor inactive may not be entirely accurate

767, pubmed.ncbi.nlm.nih.gov/39941438/,

Finally, GLP-1 receptor agonists do not seem to affect negatively the cardiovascular risk in patients with T2D, but an ultimate all-clear regarding the risk of cardiovascular events, pancreatitis, or pancreatic cancer, which may be caused by incretin-mimetic drugs, cannot be given as there is scattered evidence for these side effects

Due to risks for decreased bioavailability of birth control pills, the manufacturer of Mounjaro (tirzepatide) recommends that patients either use barrier contraception for four weeks after initiation or dosage increase or switch to a non-oral contraceptive
