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Semaglutide is usually administered as a single dose (2.4 mg) subcutaneous injection once a week

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Clinical research shows average reductions of one to two pounds per week during the initial month, though individual results depend heavily on baseline metabolism, physical activity, and adherence to healthy eating patterns

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The standard protocol in clinical trials started at lower doses (1mg or 2mg weekly) and titrated upward every four weeks to minimize gastrointestinal side effects

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Despite this, no increase in heart attacks or serious heart problems has been reported so far

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