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In Eli Lilly's pivotal Phase 3 ATTAIN clinical trialsthe studies that led to FDA approvalparticipants taking orforglipron achieved average body weight reductions of approximately 7.9% to 8.7% over 36 to 40 weeks, depending on the dosing

Sources: JPML Statistics Report, July 1, 2026, JAMA Ophthalmology Hathaway et al

This is not all the information you need to know about weight loss drugs or their side effects for safe and effective use and does not take the place of your doctors directions

This means current practices appear compliant, but there have been previous instances of noncompliance with LegitScript standards

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