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Here, we test whether GLP-1RAs alter alcohols peripheral pharmacokinetics as a potential mechanism of action for their alcohol intake suppressive effects

The use of GLP-1 medications has become a cultural health norm, with more than 12% of Americans having been prescribed them or currently taking them

Methods PAM amidation activity, postprandial GLP-1 levels, and the incretin effect were measured in carriers of PAM T2D-risk alleles and matched non-carriers from the Oxford Biobank in a prospective observational study and in Danish cohorts

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