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Drives glucose-dependent insulin secretion, suppresses glucagon, slows gastric emptying, and signals satiety via hypothalamic and brainstem pathways

Finding the balance between effective and tolerable doses often requires some experimentation within protocol guidelines

Christina Boots, a reproductive endocrinology and infertility specialist at Northwestern Medicine in Chicago, said she's not sure if the recommendation for a backup form of contraception came from data seen during phase I or phase II clinical trials or if researchers saw more incidental pregnancies in those early studies