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1 Introduction Diabetes mellitus (DM) is a metabolic disease characterized by hyperglycemia (elevated blood glucose), which is caused by a lack of insulin or failure of insulin, resulting in cells being unable to absorb glucose, thus increasing blood glucose levels

Owing to limited safety data during pregnancy, careful risk-benefit assessment and pre-pregnancy counseling are imperative

There is no ground truth, one NIH program officer said

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It has been well established that in both type 1 diabetes (T1D) and T2D, a chronic low-grade inflammatory state contributes to DKD, in part due to hyperglycemic insults