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Mounjaro is approved for type 2 diabetes management, while Zepbound is approved for chronic weight management in adults with obesity or in those overweight with a weight-related health condition, such as high blood pressure, high cholesterol, or type 2 diabetes

Thus, these in vitro findings indicate that the beneficial effect of incretin receptor agonists on fibrosis progression in MASLD patients is likely to be mediated indirectly through improvements in body weight, inflammation, and insulin resistance, rather than through the direct action on hepatic parenchymal or non-parenchymal cells