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Diabetes Obes Metab (2022) 24 Suppl 1:1726
But proponents of the medications have pointed out that some people cant achieve a healthy weight through diet and exercise alone, perhaps due to factors like genetics or stress

[DOI] [PMC free article] [PubMed] [Google Scholar] 347.Merchenthaler I., Lane M., Shughrue P

Versus semaglutide, tirzepatide 10 and 15 mg were associated with numerically greater reductions in FPG and HbA1c (Table 2)
TRIUMPH-4 answered that in April 2026