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13 Further research is needed to investigate the interconnected pathophysiologic roles of glucagon, GLP-1, and GIP while determining the niche for twincretin therapy in T2DM

This is the point where the bacterial strains should be well established, metabolite production should be consistent, and the downstream effects on GLP-1 should be at their peak
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He also has a history of hypertension and dyslipidaemia that are being successfully managed with amlodipine, low-dose aspirin and atorvastatin

10.1371/journal.pone.0087488 31
