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These changes were accompanied by preservation of structural proteins including aggrecan and collagen II, along with reduced caspase-3mediated apoptosis, suggesting a coordinated reduction in glycation-driven cellular stress and tissue degradation

and awake tracheal extubation." 2.5 Comparison with Other Guidelines: 2.5.1 ASA Guidelines: A multisociety consensus for the perioperative management of patients taking GLP1 RAs was developed by representatives from: The American Society of Anesthesiologists The American Gastroenterological Association The American Society for Metabolic and Bariatric Surgery The International Society of Perioperative Care of Patients with Obesity The Society of American Gastrointestinal and Endoscopic Surgeons Recommendation 1 [2] : Consider variables that increase the risk of delayed gastric emptying and aspiration with the periprocedural use of GLP-1RA: - The escalation phase of the medication- Higher doses- Weekly dosing- The presence of gastrointestinal symptoms (nausea, vomiting, abdominal pain, dyspepsia, and constipation) suggestive of delayed gastric emptying- Other medical conditions that may delay gastric emptying

Tirzepatide for Obstructive Sleep Apnea: A Novel Therapeutic Promise and the Perioperative Considerations

Bartholome R, Salden B, Vrolijk MF, et al

doi: 10.1016/j.regpep.2008.07.003