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Mol Cell Biochem 350:1327

Thus, GLP-1R-targeted nanotherapies for T2DM are primarily designed to enhance therapeutic convenience through oral or infrequent dosing and to improve efficacy through targeted pancreatic delivery, with the potential to substantially improve clinical outcomes
HbA1c (glycated haemoglobin), which reflects average blood glucose over the preceding 23 months, typically shows measurable improvement by 1216 weeks
Semaglutide GLP-1 has demonstrated significant efficacy for weight loss in non-diabetic individuals through various clinical trials and studies
The molecular mechanisms by which autophagy is confirmed to be involved in the occurrence and development of UC are shown in Fig
