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Multiple FDA-reviewed GRAS notices did not reveal evidence of harmful gut effects at intended use levels, although none of the studies directly assessed gut bacteria composition in humans
Barboza JJ et al
These results showed that TG-induced ER stress triggered nuclear translation of NF-B, contributing to pro-inflammatory cytokine transcription and subsequently promoting an ECM catabolic process
Neary, N
Bioorg Med Chem Lett 23:40114018 Cornell S (2012) Differentiating among incretin therapies: a multiple-target approach to type 2 diabetes
