tirzepatide alzheimers reduces food intake and appetite, and affects brain functioning, more than placebo and liraglutide Tirzepatide prevents neurodegeneration through multiple

Thondam et al

Clinical trials named SURMOUNT tested tirzepatide for weight loss, while STEP trials tested semaglutide for weight loss

Placing a child under 12 on a weight-loss injection adds a new social dimension: peers and family members may ask questions, and the child may internalize an identity of "needing medication to control eating." This is not a trivial concern

The weight loss itself improves fertility in individuals with obesity related infertility, potentially leading to unplanned pregnancy

Oral medications with narrow therapeutic windows - certain antibiotics, thyroid medications, anticoagulants - can be affected by the gastric emptying delay that GLP-1 medications cause