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We now turn to human studies for clinical evidence

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Falling estrogen levels mean we lose muscle faster, store more fat around our middles, and become more insulin-resistant

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Key Background GLP-1 drugs, which were first designated for diabetes treatment, have become wildly popular in the last few years due to their effectiveness and FDA approval as a weight loss drug

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However, due to the effect on gastric emptying there could be minimal effects with absorption of T2DM drugs when administered with semaglutide

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These findings raise the question of how a TTE analysis would perform in a broader population with more heterogeneous medication patterns

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