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Who should not use GLP-1 therapy

Six injections with equal spacing were made on ventral and dorsal sides of stomach

In this context, the aim of the present document is to summarize, in the form of a narrative literature review, the currently available data on the main mechanisms of action of GIP/GLP-1 co-agonists and the clinical effects of tirzepatide evaluated in various clinical trials

GLP-1 receptor agonists do not increase the risk of hypoglycemia relative to placebo (48)

3 mg/kg) or vehicle respectively (combined with acute PVN injections of Bicuculline Methiodide 3 min prior to CNO administration when stated)