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A glucagon-like peptide-1 (GLP-1) analogue, liraglutide, upregulates nitric oxide production and exerts anti-inflammatory action in endothelial cells

The conversation typically sounds like this: I lost 30 pounds and I feel healthier, but I dont want sex anymore . At first glance, there doesnt seem to be a diagnosable problem: Patients labs look fine, their heart health has improved, their blood sugar is better, and their blood pressure dropped

GLP-1 RAs showed significant reductions in all anthropometric parameters, while SGLT2is was observed to improve WHR and AGF ratio (in addition to reduced body weight observed with SGLT2is/metformin combination)

Semaglutide, another GLP-1 analog, has also shown efficacy in MASH (see semaglutide for MASH)

Your metabolic health and mental health are connected